HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Aminopyridine → N-(2-Chloroethyl)-N'-(3-pyridinyl)urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Aminopyridine | HCID 10009 | — |
| Reactant | 2-Chloroethyl isocyanate | HCID 16035 | — |
| Product | N-(2-Chloroethyl)-N'-(3-pyridinyl)urea | HCID 256330 | 99.9% |
Reaction Steps
To a solution of 150 g of 3-aminopyridine dissolved in 1000 ml of tuluene, 176 g of 2-chloroethylisocyanate was added dropwise over 30 minutes under cooling. After stirring at room temperature for 5 hours, the precipitated crystals were collected by filtration to give 318 g of N-(2-chloroethyl)-N'-(3-pyridyl) urea.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04886817 |
| Source dataset | uspto-grants-1989_12 |
| ORD ID | ord-a549fca4347c4b76a0ce5858626b86a1 |
| Source note | uspto-grants-1989_12 |