HuagongsheHuagongshe Chemistry Print Report · For research reference only
rel-(3R,4S)-4-Methyl-3-pyrrolidinamine → HCID 14304604, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | rel-(3R,4S)-4-Methyl-3-pyrrolidinamine | HCID 10329256 | — |
| Reactant | 1-Cyclopropyl-5,6,7,8-tetrafluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | HCID 13825515 | — |
| Solvent | O-Xylene | HCID 7237 | — |
| Product | HCID 14304604 | HCID 14304604 | — |
Reaction Steps
In the same manner as described in Example 5, a mixture of 1-cyclopropyl-5,6,7,8-tetrafluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid, trans-3-amino4-methylpyrrolidine, and xylene was refluxed for 3 hours to give 7-(trans-3-amino-4-methyl-1-pyrrolidinyl)-1-cyclopropyl-5,6,8-trifluoro-1,4-dihydro-4-oxoquinoline3-carboxylic acid, m.p. 255°-256° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04886810 |
| Source dataset | uspto-grants-1989_12 |
| ORD ID | ord-59c77e1dbb0b4e40ab65191382fa8d9e |
| Source note | uspto-grants-1989_12 |