HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 477043Generated: October 31, 2026
N-Benzylglycine ethyl ester → Ethyl 1-benzyl-1,4,5,6-tetrahydrocyclopenta[b]pyrrole-2-carboxylate
https://huagongshe.com/reaction/477043
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | N-Benzylglycine ethyl ester | HCID 80908 | — |
| Reactant | 2-Chlorocyclopent-1-ene-1-carbaldehyde | HCID 12389970 | — |
| Product | Ethyl 1-benzyl-1,4,5,6-tetrahydrocyclopenta[b]pyrrole-2-carboxylate | HCID 13592288 | — |
Reaction Steps
25 g (0.191 mol) of 2-chloro-1-formylcyclopent-1-ene are added to 73.9 g (0.382 mol) of N-benzylglycine ethyl ester at room temperature and the mixture is then heated to 110° C. Working-up is carried out as indicated in Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04886827 |
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| Source dataset | uspto-grants-1989_12 |
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| ORD ID | ord-9fb186bfd885412e9d8c59dc2f79687d |
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| Source note | uspto-grants-1989_12 |
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