Methyl 5-(4-methoxy-3-nitrophenyl)-3-pyridinecarboxylate → HCID 19837271, compound

Participants

Reaction Conditions

Reaction Steps

990 mg of the resulting nitro compound was dissolved in 60 ml of ethyl acetate, and 0.3 g of 10% palladium-carbon was added. The nitro compounds was thus catalytically reduced with stirring at 50° C. The catalyst was removed in a customary manner, and the resulting yellow crystals were recrystallized from methylene chloride-ether to give 723 mg (yield 81%) of methyl 5-(3-amino-4-methoxyphenyl)nicotinate as pale yellow needles having a melting point of 98° to 99° C.

Provenance & Evidence