HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 4-(2-aminoethyl)benzoate → HCID 14076218, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 4-(2-aminoethyl)benzoate | HCID 12945884 | — |
| Reactant | N-[5-(bromoacetyl)-4-methyl-1,3-thiazol-2-yl]acetamide | HCID 19974111 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 14076218 | HCID 14076218 | — |
Reaction Steps
Prepared analogously to Example 3 by reaction of 2-(4-carboethoxyphenyl)ethylamine and stoichiometric amounts of triethylamine with 2-acetylamino-4-methyl-5-bromoacetyl-thiazole, followed by reduction and purification of the base on a silica gel column using ethyl acetate/methanol=19:1 as eluant and trituration with ether.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04886814 |
| Source dataset | uspto-grants-1989_12 |
| ORD ID | ord-0e894a067615495c877262eae0316c21 |
| Source note | uspto-grants-1989_12 |