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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 477109Generated: October 27, 2026

Methyl 2-(4-(2-oxopropyl)phenoxy)acetate → N-[2-(4-Carbomethoxymethoxyphenyl)-1-methylethyl]-2-hydroxy-2-(thiazol-4-yl)ethanamine

https://huagongshe.com/reaction/477109

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-(4-(2-oxopropyl)phenoxy)acetateHCID 13851156—
Reactant2-Amino-1-(thiazol-4-yl)ethanolHCID 19974168—
ProductN-[2-(4-Carbomethoxymethoxyphenyl)-1-methylethyl]-2-hydroxy-2-(thiazol-4-yl)ethanamineHCID 19974207—

Reaction Steps

Prepared analogously to Example 13 by reaction of 2-hydroxy-2-(thiazol-4-yl)ethylamine with 1-(4-carbomethoxymethoxyphenyl)propan-2-one followed by purification of the base on a silica gel column using ethyl acetate/methanol=8:2 as eluant.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04886814
Source datasetuspto-grants-1989_12
ORD IDord-ff23ba13469049b3a1483430318ab2bd
Source noteuspto-grants-1989_12