HuagongsheHuagongshe Chemistry Print Report · For research reference only
α-(Aminomethyl)-2-methyl-4-thiazolemethanol → N-[2-(4-(2-Carbomethoxy-1-methylethenyl)phenyl)-1-methylethyl]-2-hydroxy-2-(2-methyl-thiazol-4-yl)ethanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | α-(Aminomethyl)-2-methyl-4-thiazolemethanol | HCID 16768496 | — |
| Reactant | 1-[4-(2-Carbomethoxy-1-methylethenyl)phenyl]propan-2-one | HCID 54548003 | — |
| Product | N-[2-(4-(2-Carbomethoxy-1-methylethenyl)phenyl)-1-methylethyl]-2-hydroxy-2-(2-methyl-thiazol-4-yl)ethanamine | HCID 53815041 | — |
Reaction Steps
Prepared analogously to Example 13 by reaction of 2-hydroxy-2-(2-methyl-thiazol-4-yl)ethanamine with 1-[4-(2-carbomethoxy-1-methylethenyl)phenyl]propan-2-one followed by purification of the base on a silica gel column using toluene/methanol=19:1 as eluant.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04886814 |
| Source dataset | uspto-grants-1989_12 |
| ORD ID | ord-57f44b9c89ac4702b16a81a9aaff19a6 |
| Source note | uspto-grants-1989_12 |