HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Hydroxyphenylacetone → N-[2-(4-Hydroxyphenyl)-1-methylethyl]-2-hydroxy-2-(2-trifluoromethylthiazol-4-yl)ethanamine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Hydroxyphenylacetone | HCID 7019274 | — |
| Edukt | 4-Thiazolemethanol, alpha-(aminomethyl)-2-(trifluoromethyl)- | HCID 14076239 | — |
| Produkt | N-[2-(4-Hydroxyphenyl)-1-methylethyl]-2-hydroxy-2-(2-trifluoromethylthiazol-4-yl)ethanamine | HCID 19974300 | — |
Reaktionsschritte
Prepared by analogy to Example 13 by reaction of 2-hydroxy-2-(2-trifluoromethyl-thiazol-4-yl)ethanamine with 4-hydroxyphenyl-propan-2-one followed by purification of the base on a silica gel column using chloroform/methanol=9:1 as eluant.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04886814 |
| Quelldatensatz | uspto-grants-1989_12 |
| ORD ID | ord-f26fb1f213af4f42a767a3477cc60d56 |
| Quellennotiz | uspto-grants-1989_12 |