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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 477154Generated: October 29, 2026

Borane;tetrahydrofuran → N-[2-(4-(2-Hydroxyethoxy)phenyl)-1-methylethyl]-2-(2-chloro-thiazol-4-yl)morpholine

https://huagongshe.com/reaction/477154

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBorane;tetrahydrofuranHCID 2723981—
ReactantN-[2-(4-Carbomethoxymethoxyphenyl)-1-methylethyl]-2-(2-chloro-thiazol-4-yl)morpholineHCID 19974190—
ProductN-[2-(4-(2-Hydroxyethoxy)phenyl)-1-methylethyl]-2-(2-chloro-thiazol-4-yl)morpholineHCID 19974191—

Reaction Steps

Prepared by analogy to Example 71 by reaction of N-[2-(4-carbomethoxymethoxyphenyl)-1-methylethyl]-2-(2-chloro-thiazol-4-yl)morpholine with borane/tetrahydrofuran complex (1 molar solution in tetrahydrofuran) for 60 hours.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04886814
Source datasetuspto-grants-1989_12
ORD IDord-ef0f7eb008784712a98c4926b6862060
Source noteuspto-grants-1989_12