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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 477163Generated: October 30, 2026

2-Bromo-3'-chloroacetophenone → HCID 14372863, compound

https://huagongshe.com/reaction/477163

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromo-3'-chloroacetophenoneHCID 38738—
ReactantPotassium BicarbonateHCID 516893—
ReactantN-[2-(4-Carbomethoxymethoxyphenyl)-1-methylethyl]-2-hydroxy-2-(2-trifluoromethyl-thiazol-4-yl)ethanamineHCID 14347763—
SolventAcetoneHCID 180—
ProductHCID 14372863HCID 14372863—

Reaction Steps

from N-[2-(4-carbomethoxymethoxyphenyl)-1-methylethyl]-2-hydroxy-2-(2-trifluoromethyl-thiazol-4-yl)-ethanamine (pair of diasteromers A) with 3-chloro-phenacyl bromide and potassium hydrogen carbonate in acetone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04886814
Source datasetuspto-grants-1989_12
ORD IDord-d851b612a2ed4e05a641badc3daee82e
Source noteuspto-grants-1989_12