1,3-Difluoro-2-nitrobenzene → 2-(2-Chloro-4-trifluoromethylphenoxy)-6-fluoronitrobenzene

HRID 477269Notes

Reaction equation

HRID 477269 reaction equation
F[C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([F:8])[C:3]=1[N+:9]([O-:11])=[O:10].[Cl:12][C:13]1[CH:18]=[C:17]([C:19]([F:22])([F:21])[F:20])[CH:16]=[CH:15][C:14]=1[OH:23]>>[Cl:12][C:13]1[CH:18]=[C:17]([C:19]([F:20])([F:21])[F:22])[CH:16]=[CH:15][C:14]=1[O:23][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([F:8])[C:3]=1[N+:9]([O-:11])=[O:10]

Participants

3

Reactant 2

HCID 879221,3-Difluoro-2-nitrobenzeneHCID 27366032-Chloro-4-(trifluoromethyl)phenol

Product 1

HCID 541374142-(2-Chloro-4-trifluoromethylphenoxy)-6-fluoronitrobenzene

Procedure

This material was prepared in 47% yeild from 2,6-difluoronitrobenzene and 2-chloro-4-trifluoromethylphenol following the general procedure outlined in Example 104. The product was isolated as an oil which was characterized by IR and 1H NMR spectroscopy.

Workup

  1. customThe product was isolated as an oil which

Sources & evidence

ORD record
ord-c3c69ad5bdc4437c83e561742fd4cf3e
Source dataset
uspto-grants-1989_12
Patent number
US04886883

Reaction notes

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