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1-Phenyl-1,2-propanedione → 4-Dimethylamino-1-phenyl-3-butene-1,2-dione
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-Phenyl-1,2-propanedione | HCID 11363 | — |
| 反応物 | Dimethylformamide diethylacetal | HCID 70913 | — |
| 反応物 | Ethyl 4-(dimethylamino)-2-oxo-but-3-enoate | HCID 2777802 | — |
| 生成物 | 4-Dimethylamino-1-phenyl-3-butene-1,2-dione | HCID 54572896 | — |
反応手順
The procedure is as in Example 2 for the preparation of ethyl 4-dimethylamino-2-oxo-3-butenoate, starting with 1-phenyl-1,2-propanedione (25 g) and N,N-dimethylformamide diethyl acetal (28.3 g). After purification by chromatography on a silica column with ethyl acetate as eluent, 4-dimethylamino-1-phenyl-3-butene-1,2-dione (9.3 g), m.p. 88° C., is obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04886835 |
| 出典データセット | uspto-grants-1989_12 |
| ORD ID | ord-50a8ceb5ef524db69a48d2451b8719bd |
| 出典メモ | uspto-grants-1989_12 |