HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 477428Generated: October 30, 2026
p-Toluenesulfonic acid → HCID 14997821, compound
https://huagongshe.com/reaction/477428
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | Gamma-Butyrolactone | HCID 7302 | — |
| Reactant | 1-Decanol | HCID 8174 | — |
| Reactant | Sodium Acetate | HCID 517045 | — |
| Solvent | Hexane | HCID 8058 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 14997821 | HCID 14997821 | 17.7% |
Reaction Steps
To a mixture of 10 ml of gamma-butyrolactone and 40 ml of 1-decanol was added a crystal of p-toluenesulfonic acid. The reaction mixture was heated at 150° C. for 72 hours with stirring, cooled to room temperature, and then treated with 10 mg of sodium acetate. Flash chromatography (silica; 4:1 hexane:ethyl acetate eluent) afforded 5.6 g (17.7%) of 4-hydroxybutanoic acid, n-decyl ester as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04888328 |
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| Source dataset | uspto-grants-1989_12 |
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| ORD ID | ord-187d4ccf66284efab73c53879fc3962a |
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| Source note | uspto-grants-1989_12 |
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