Hydrochloric Acid → HCID 19835813, compound

Participants

Reaction Steps

By procedure analogous to that of example 4, but omitting the DMF solvent, the free base of N-[3-(diethylamino)propyl]-5-phenyl-1H-pyrazole-1-acetamide hydrochloride was prepared from 1.0g 4.3 mmol) of ethyl 5-phenyl-1H-pyrazole-1-acetate and 3-(diethylamino)propanamine. The hydrochloride salt was prepared by dissolving the free base (an oil) in ethanol, adding a solution of hydrogen chloride in anhydrous ether, and recrystallizing the resulting solid from ethanol-ether. Upon drying, the white, crystalline product collapsed to a brownish, amorphous solid.

Provenance & Evidence