1-Naphthaleneacetic Acid → HCID 3087827, compound

Participants

Reaction Steps

Using the procedure of Step C of Example 1, 0.432 g of the product of the product of Step B of Example 1, 0.484 of 1-naphthylacetic acid and 0.422 g of carbonyldiimidazole were reacted to obtain 0.718 g of trans (±) N-[2,3-dihydro-2-(1-pyrrolidinyl)-1H-inden-1-yl]-N-methyl-1-naphthalene-acetamide melting at 127° C. and then 0.655 g of the base were reacted to obtain 0.533 g of its hydrochloride melting at ≃240° C.

Provenance & Evidence