N,N-Diethylethylenediamine → HCID 19804340, compound

Participants

Reaction Steps

To an ice-cooled solution of 5-bromobenzo[b]furan-7-carboxylic acid chloride (1.5 g, 5.8 mmol) in 15 ml of CH2Cl2, there was added N,N-diethylethylenediamine (0.74 g, 6.4 mmol) in 10 ml of CH2Cl2. After stirring at ambient temperature overnight, the precipitate was collected on a filter to give the crude amide (1.14 g, 53.2%). This was recrystallized from ethanol (decolorization with charcoal) to give 0.54 g (24.8%) of the desired amide as a white solid, mp 202°-203.5° C. IR (KBr) 1675 (C=0) cm-1.

Provenance & Evidence