反应详情

The product obtained in Step 2 (1.0 g) was added to a solution of 0.29 g of sodium hydroxide in 20 ml of 80% ethanol, 1.31 g of carbon disulfide was further added, and the mixture was refluxed for 24 hours. After concentrating under reduced pressure, the residue was dissolved in 10 ml of water and the pH was adjusted to 2.0 with 1N hydrochloric acid. The formed crystals were collected by filtration and washed with 10 ml of water and 10 ml of ethanol, affording 0.7 g of the objective compound as pink crystals.

1. additionwas further added
2. temperaturethe mixture was refluxed for 24 hours
3. concentrationAfter concentrating under reduced pressure
4. dissolutionthe residue was dissolved in 10 ml of water
5. filtrationThe formed crystals were collected by filtration
6. washwashed with 10 ml of water and 10 ml of ethanol