Methyl iodide → HCID 19872252, compound

Participants

Reaction Steps

3,3-Diisobutyl-2-methyl-(3H)-indole (2.43 g, 0.01 mole) and methyl iodide (3 g, excess) were heated in a flask with condenser on a steam bath for 30 min. The excess methyl iodide was evaporated, and the resulting syrup was dissolved in a small amount of methanol and diluted to 350 mL with ether while stirring in a beaker. After stirring for 20 min., the product was filtered, washed with ether, and dried to give 3.0 g (77.8%). The NMR was good. (MW 385.33)

Provenance & Evidence