HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Chloride → 5-(benzylsulfanyl)-4H-1,2,4-triazol-3-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Chloride | HCID 7503 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 5-amino-1H-1,2,4-triazole-3-thiol | HCID 178509296 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 5-(benzylsulfanyl)-4H-1,2,4-triazol-3-amine | HCID 737272 | 90.6% |
Reaction Steps
3-Amino-5-mercapto-1,2,4-triazole (40.36 g) was treated at room temperature with sodium hydroxide (13.9 g) in ethanol (450 ml), and benzyl chloride (44.3 g) was added. The mixture was stirred overnight, and was then filtered. The ethanol was evaporated off, and the residue was recrystallised from ethyl acetate to give 64.97 g of the desired product, mp 104° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04889553 |
| Source dataset | uspto-grants-1989_12 |
| ORD ID | ord-b82cfc36a6374223bdd0d890c06b2c86 |
| Source note | uspto-grants-1989_12 |