2,6-Dichloroaniline → HCID 19872285, compound

HRID 477734Notes

Reaction equation

HRID 477734 reaction equation
[C:1]([N:4]1[C:8]([NH2:9])=[N:7][C:6]([S:10](Cl)(=[O:12])=[O:11])=[N:5]1)(=[O:3])[CH3:2].[Cl:14][C:15]1[CH:21]=[CH:20][CH:19]=[C:18]([Cl:22])[C:16]=1[NH2:17]>N1C=CC=CC=1>[NH+:17]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:16]=1.[Cl:14][C:15]1[CH:21]=[CH:20][CH:19]=[C:18]([Cl:22])[C:16]=1[NH:17][S:10]([C:6]1[N:7]=[C:8]([NH2:9])[N:4]([C:1](=[O:3])[CH3:2])[N:5]=1)(=[O:12])=[O:11]

Participants

4

Reactant 2

HCID 118462,6-DichloroanilineHCID 142551231-Acetyl-5-amino-1H-1,2,4-triazole-3-sulfonyl chloride

Product 1

HCID 19872285HCID 19872285, compoundYield 94.7%

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Conditions

Temperature
60 °C

Procedure

The product of stage (c) (54 g) was treated with 2,6-dichloroaniline (42.63 g) in pyridine (350 ml) and was stirred at 60° C. for 12 hours. After cooling, the product was filtered off, washed with a little pyridine and ether, and was dried in vacuum to give 53.6 g of the desired product, mp 213°-215° C.

Workup

  1. temperatureAfter cooling
  2. filtrationthe product was filtered off
  3. washwashed with a little pyridine and ether
  4. customwas dried in vacuum

Sources & evidence

ORD record
ord-fe087008e41645978237e25276f12840
Source dataset
uspto-grants-1989_12
Patent number
US04889553

Reaction notes

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