Acetic Anhydride → HCID 14276850, compound

HRID 477737Notes

Reaction equation

HRID 477737 reaction equation
[NH2:1][C:2]1[N:6]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[N:5]=[C:4]([S:13][CH2:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[N:3]=1.[C:21](OC(=O)C)(=[O:23])C>C(O)=O>[CH2:14]([S:13][C:4]1[N:3]=[C:2]([NH:1][CH:21]=[O:23])[N:6]([C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=2)[N:5]=1)[C:15]1[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 15578960HCID 15578960, compound

Product 1

HCID 14276850HCID 14276850, compound

Reagents, catalysts & solvents 1

HCID 284Formic AcidSolvent

Procedure

5-Amino-3-benzylthio-1-phenyl-1,2,4-triazole (45 g) was suspended in acetic anhydride (31 ml) and formic acid (16.09 ml), and the mixture was stirred for 1 hour at 80° C. The solvents were then removed, and the residue was recrystallised from ethyl acetate to give 35.4 g of the desired product, mp 94° C.

Workup

  1. customThe solvents were then removed
  2. customthe residue was recrystallised from ethyl acetate

Sources & evidence

ORD record
ord-68c364812c9541469576dfd1e1016d6e
Source dataset
uspto-grants-1989_12
Patent number
US04889553

Reaction notes

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