化工社化工社 化学情報印刷レポート · 研究参考用
Benzyl Chloride → 5-(benzylsulfanyl)-4H-1,2,4-triazol-3-amine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzyl Chloride | HCID 7503 | — |
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | HCID 178509066 | HCID 178509066 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 5-(benzylsulfanyl)-4H-1,2,4-triazol-3-amine | HCID 737272 | 90.6% |
反応手順
5-Amino-3-mercapto-1,2,4-triazole (40.36 g) in ethanol (450 ml) was treated at room temperature with solid sodium hydroxide (13.9 g), and benzyl chloride (44.3 g) was added dropwise. The solution was stirred overnight, filtered, and the residue was recrystallised from ethyl acetate and dried to give 64.97 g of desired product, mp 104° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04889553 |
| 出典データセット | uspto-grants-1989_12 |
| ORD ID | ord-6fd3a55b65164c879b0f4f5236978b3e |
| 出典メモ | uspto-grants-1989_12 |