HCID 677942, compound → HCID 677495, compound

HRID 477782Notes

Reaction equation

HRID 477782 reaction equation
C[O:2][C:3]1[CH:18]=[CH:17][C:6]2[O:7][CH2:8][C:9]3[CH:16]=[CH:15][CH:14]=[CH:13][C:10]=3[C:11](=[O:12])[C:5]=2[CH:4]=1.Cl.N1C=CC=CC=1>O>[OH:2][C:3]1[CH:18]=[CH:17][C:6]2[O:7][CH2:8][C:9]3[CH:16]=[CH:15][CH:14]=[CH:13][C:10]=3[C:11](=[O:12])[C:5]=2[CH:4]=1

Participants

4

Reactant 2

HCID 677942HCID 677942, compoundHCID 10176127Pyridinium chloride

Product 1

HCID 677495HCID 677495, compoundYield 79.7%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
180 °C

Procedure

A mixture of 20 g of 2-methoxy-6,11-dihydrodibenz[b,e]oxepin-11-one and 150 g of pyridine hydrochloride is stirred with heating at 180° C for 2 hours. The solution is poured into 2 liter of water with stirring to give 15 g of 2-hydroxy-6,11-dihydrodibenz[b,e]oxepin-11-one. Mass spectrum m/z: 226(M+), melting point: 165°-166° C. (recrystallized from ethanol).

Workup

  1. stirringwith stirring

Sources & evidence

ORD record
ord-2b2c9985ff50414d9021007233e6ec85
Source dataset
uspto-grants-1989_12
Patent number
US04889858

Reaction notes

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