Diethyl Ether → HCID 86620054, compound

HRID 477796Notes

Reaction equation

HRID 477796 reaction equation
[C:1]([OH:8])(=[O:7])/[CH:2]=[CH:3]\[C:4]([OH:6])=[O:5].C(OCC)C>C(O)C>[OH2:5].[C:1]([OH:8])(=[O:7])/[CH:2]=[CH:3]\[C:4]([OH:6])=[O:5]

Participants

4

Reactant 2

HCID 3283Diethyl EtherHCID 444266Maleic Acid

Product 1

HCID 86620054HCID 86620054, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a solution of 1.4 g of the above free base in 10 ml of ethanol is added 0.8 g of maleic acid to dissolve and then diethyl ether is added. Precipitated crystals are collected by filtration and recrystallized from ethanol-diethyl ether to give 3/2 maleate monohydrate of the objective compound (compound 1). Melting point 133°-135° C.

Workup

  1. dissolutionto dissolve
  2. customPrecipitated crystals
  3. filtrationare collected by filtration
  4. customrecrystallized from ethanol-diethyl ether

Sources & evidence

ORD record
ord-1fe9e5f8d6aa4d49a53e592762f2f2d2
Source dataset
uspto-grants-1989_12
Patent number
US04889858

Reaction notes

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