HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyproheptadine → 2-[(4-Methylpiperazin-1-yl)methyl]morpholine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyproheptadine | HCID 2913 | — |
| Reactant | 1-Methylpiperazine | HCID 53167 | — |
| Reactant | 4-Benzyl-2-(chloromethyl)morpholine | HCID 2801562 | — |
| Product | 2-[(4-Methylpiperazin-1-yl)methyl]morpholine | HCID 14627568 | — |
Reaction Steps
By the use of 2-chloromethyl-4-benzylmorpholine and N-methylpiperazine, the reactin is similarly carried out as Reference example 2 to give 2-(4-methyl-1-piperazinylmethyl) morpholine.trihydrochloride as white crystals, melting at 210°-212° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04889857 |
| Source dataset | uspto-grants-1989_12 |
| ORD ID | ord-169f0a72445b4186ab52fd476f25a5a6 |
| Source note | uspto-grants-1989_12 |