1-Piperazinecarboxaldehyde → HCID 88622674, compound

HRID 477821Notes

Reaction equation

HRID 477821 reaction equation
[Cl:1][CH2:2][CH:3]1[O:8][CH2:7][CH2:6][N:5](CC2C=CC=CC=2)[CH2:4]1.[CH:16]([N:18]1[CH2:23][CH2:22][NH:21][CH2:20][CH2:19]1)=[O:17]>>[ClH:1].[ClH:1].[CH:16]([N:18]1[CH2:23][CH2:22][N:21]([CH2:2][CH:3]2[O:8][CH2:7][CH2:6][NH:5][CH2:4]2)[CH2:20][CH2:19]1)=[O:17]

Participants

3

Reactant 2

HCID 821911-PiperazinecarboxaldehydeHCID 28015624-Benzyl-2-(chloromethyl)morpholine

Product 1

HCID 88622674HCID 88622674, compound

Procedure

By the use of 2-chloromethyl-4-benzylmorpholine and N-formylpiperazine, the reaction is similarly carried out as Reference example 2 to give 2-(4-formyl-1-piperazinylmethyl) morpholine.dihydrochloride as white crystals, melting at 243°-245° C. with decomposition.

Sources & evidence

ORD record
ord-b4696413cb8c4eaeb01434f97f6e9e7a
Source dataset
uspto-grants-1989_12
Patent number
US04889857

Reaction notes

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