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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 477842Generated: October 31, 2026

1-Cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid → HCID 10478111, compound

https://huagongshe.com/reaction/477842

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acidHCID 535414—
ReactantN-Ethyl-N-[(morpholin-2-yl)methyl]ethanamineHCID 4015074—
ProductHCID 10478111HCID 10478111—

Reaction Steps

By the use of 1-cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid and 2-(diethylaminomethyl)morpholine, the reaction is similarly carried out as Example 11 to give 1-cyclopropyl-7-[2-(diethylaminomethyl)morpholino]-6,8-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid, melting at 155°-157° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04889857
Source datasetuspto-grants-1989_12
ORD IDord-adf3b18fa57d43ec8dd70afa8b3b70f5
Source noteuspto-grants-1989_12