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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 477843Generated: October 31, 2026

1-Cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid → HCID 19834962, compound

https://huagongshe.com/reaction/477843

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acidHCID 535414—
Reactant2-[(Pyrrolidin-1-yl)methyl]morpholineHCID 14627502—
ProductHCID 19834962HCID 19834962—

Reaction Steps

By the use of 1-cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid and 2-(1-pyrrolidinylmethyl)morpholine, the reaction is similarly carried out as Example 11 to give 1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-7-[2-(1-pyrrolidinylmethyl)morpholino]quinoline-3-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04889857
Source datasetuspto-grants-1989_12
ORD IDord-c3abb105c7714263a0aa4554630e7763
Source noteuspto-grants-1989_12