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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 477857Generated: October 31, 2026

Dimethylamine → 7-[2-(Dimethylaminomethyl)morpholino]-1-ethyl-6,8-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid

https://huagongshe.com/reaction/477857

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylamineHCID 674—
Reactant7-(2-Chloromethylmorpholino)-1-ethyl-6,8-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acidHCID 14652631—
Product7-[2-(Dimethylaminomethyl)morpholino]-1-ethyl-6,8-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acidHCID 14652605—

Reaction Steps

By the use of 7-(2-chloromethylmorpholino)-1-ethyl-6,8-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid and dimethylamine, the reaction is similarly carried out as Example 34 to give 7-[2-(dimethylaminomethyl)morpholino]-1-ethyl-6,8-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid, melting at 185°-188° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04889857
Source datasetuspto-grants-1989_12
ORD IDord-a95cdccfe11142ea851c7a992fe76ffd
Source noteuspto-grants-1989_12