Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,2-Diiodoethane → 2-(4-Trifluoromethylphenyl)-5-iodothiazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,2-Diiodoethane | HCID 12224 | — |
| 반응물 | 2-(4-(Trifluoromethyl)phenyl)thiazole | HCID 14601969 | — |
| 반응물 | Butyllithium | HCID 178418339 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 용매 | Hexane | HCID 8058 | — |
| 생성물 | 2-(4-Trifluoromethylphenyl)-5-iodothiazole | HCID 14601970 | 46.5% |
반응 단계
In a manner similar to Step C of Example 1, the reaction of 5.45 grams (0.0238 mole) of 2-(4-trifluoromethylphenyl)thiazole, 9.5 ml of a 2.5 M solution of n-butyllithium in hexane, and 6.71 grams (0.0238 mole) of 1,2-diiodoethane in 40 ml of diethyl ether produced 3.93 grams of 2-(4-trifluoromethylphenyl)-5-iodothiazole as a solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04889867 |
| 출처 데이터셋 | uspto-grants-1989_12 |
| ORD ID | ord-952bda2a830d45e2b3066c627e9e143c |
| 출처 메모 | uspto-grants-1989_12 |