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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 477983Generated: October 30, 2026

2-Methylpropan-2-olate → 5-(p-Cyanophenyl)-7,8-dihydroimidazo[1,5-a]pyridine

https://huagongshe.com/reaction/477983

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methylpropan-2-olateHCID 4574913—
Reactant1-(p-cyanophenylmethyl)-5-(2-formylethyl)-1H-imidazoleHCID 15294731—
SolventEthanolHCID 702—
Product5-(p-Cyanophenyl)-7,8-dihydroimidazo[1,5-a]pyridineHCID 15294718—

Reaction Steps

A solution of 0.24 g of 1-(p-cyanophenylmethyl)-5-(2-formylethyl)-1H-imidazole in 10 ml of anhydrous ethanol is refluxed under nitrogen for 2 h with 20 mg of potasssium tert-butoxide, cooled and evaporated to yield the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04889861
Source datasetuspto-grants-1989_12
ORD IDord-2ed022ccdcd542299bb241c364d31a34
Source noteuspto-grants-1989_12