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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 478051Generated: October 27, 2026

2-(Chloromethyl)quinoline → HCID 178465626, compound

https://huagongshe.com/reaction/478051

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Chloromethyl)quinolineHCID 20394—
ReactantHCID 178513185HCID 178513185—
ProductHCID 178465626HCID 17846562665%

Reaction Steps

In a similar manner to Example 1A and using 2-chloromethyl quinoline, 3-(2-quinolinylmethoxy)acetophenone is prepared (13.1 g, m.p. 57°-59° C., 47% yield). This product is reacted with amino guanidine bicarbonate as in 1B above to give 2.35 g of product (65% yield), m.p. 168°-170° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04889935
Source datasetuspto-grants-1989_12
ORD IDord-fd138a62c7684a99a2cd684fab6d1b45
Source noteuspto-grants-1989_12