HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl trifluoroacetate → 2-N-trifluoroacetyl-6-N-benzyloxycarbonyl-lysine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl trifluoroacetate | HCID 9794 | — |
| Reactant | epsilon-(Benzyloxycarbonyl)-L-lysine | HCID 1715626 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-N-trifluoroacetyl-6-N-benzyloxycarbonyl-lysine | HCID 86585333 | — |
Reaction Steps
100.0 g (356.7 mmol) of 6-N-benzyloxycarbonyl-L-lysine is dissolved in a mixture that consists of 1000 ml of trifluoroacetic acid ethyl ester and 500 ml of ethanol, and it is stirred for 24 hours at room temperature. It is evaporated to the dry state, and the residue is crystallized from diisopropyl ether.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06641797B2 |
| Source dataset | uspto-grants-2003_11 |
| ORD ID | ord-aee2460350b940a696b357cf09080bc7 |
| Source note | uspto-grants-2003_11 |