Methyl iodide → 3-{4-[2-(Tert-butoxycarbonyl-heptyl-amino)-ethyl]-phenyl}-2-methoxy-propionic acid methyl ester

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Reaction Steps

Synthesized from 3-{4-[2-(tert-butoxycarbonyl-heptyl-amino)-ethyl]-phenyl}-2-hydroxy-propionic acid ethyl ester using a procedure analogous to that used for Example 47 and substituting methyl iodide as the electrophile to give 3-{4-[2-(tert-butoxycarbonyl-heptyl-amino)-ethyl]-phenyl}-2-methoxy-propionic acid methyl ester as a clear oil containing a mixture of methyl and ethyl ester (48 mg, 18%).

Provenance & Evidence