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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 47824Generated: October 26, 2026

Phenol → 3-{4-[2-(tert-Butoxycarbonyl-heptyl-amino)-ethyl]-phenyl}-2-phenoxy-propionic Acid Ethyl Ester

https://huagongshe.com/reaction/47824

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenolHCID 996—
Reactant3-{4-[2-(Tert-butoxycarbonyl-heptyl-amino)-ethyl]-phenyl}-2-hydroxy-propionic acid ethyl esterHCID 69883772—
Product3-{4-[2-(tert-Butoxycarbonyl-heptyl-amino)-ethyl]-phenyl}-2-phenoxy-propionic Acid Ethyl EsterHCID 69884481—

Reaction Steps

Synthesized from 3-{4-[2-(tert-butoxycarbonyl-heptyl-amino)-ethyl]-phenyl}-2-hydroxy-propionic acid ethyl ester using a procedure analogous to that used for Example 50 and substituting phenol as the nucleophile to give an approximate 1:1 mixture of ethyl and methyl ester as a clear film (35 mg, 61%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06699904B2
Source datasetuspto-grants-2004_03
ORD IDord-b8d16e2dabe046f3ac64fb4ff4f5a33f
Source noteuspto-grants-2004_03