HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiomorpholine → Rac-cis-(3,5-bis-trifluoromethyl-phenyl)-(3-phenyl-4-thiomorpholin-4-yl-piperidin-1-yl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiomorpholine | HCID 67164 | — |
| Reactant | 3,5-Bis(trifluoromethyl)benzoyl chloride | HCID 101856 | — |
| Reactant | 1-Benzyl-3-phenylpiperidin-4-one | HCID 11817956 | — |
| Product | Rac-cis-(3,5-bis-trifluoromethyl-phenyl)-(3-phenyl-4-thiomorpholin-4-yl-piperidin-1-yl)-methanone | HCID 131724170 | — |
Reaction Steps
The title compound, MS: m/e=503.2 (M+H+), was prepared in accordance with the general method of example 26 from 1-benzyl-3-phenyl-piperidin-4-one, thiomorpholine and 3,5-bistrifluoromethyl-benzoyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06642226B2 |
| Source dataset | uspto-grants-2003_11 |
| ORD ID | ord-f5f05c93488447db931ac332dcc9fe01 |
| Source note | uspto-grants-2003_11 |