HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methylpiperazine → Rac-cis-(3,5-dichloro-phenyl)-[4-(4-methyl-piperazin-1-yl)-3-phenyl-piperidin-1-yl]-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methylpiperazine | HCID 53167 | — |
| Reactant | 3,5-Dichlorobenzoyl chloride | HCID 76191 | — |
| Reactant | 1-Benzyl-3-phenylpiperidin-4-one | HCID 11817956 | — |
| Product | Rac-cis-(3,5-dichloro-phenyl)-[4-(4-methyl-piperazin-1-yl)-3-phenyl-piperidin-1-yl]-methanone | HCID 131724194 | — |
Reaction Steps
The title compound, MS: m/e=432.2 (M+H+), was prepared in accordance with the general method of example 26 from 1-benzyl-3-phenyl-piperidin-4-one, N-methyl-piperazine and 3,5-dichloro-benzoyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06642226B2 |
| Source dataset | uspto-grants-2003_11 |
| ORD ID | ord-562dc5cb667b4e47bacb53d0f6a05639 |
| Source note | uspto-grants-2003_11 |