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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 478471Generated: October 30, 2026

(4-Chlorophenyl)(cyclopropyl)methanamine → 2-Chloro-6-[(alpha-cyclopropyl-4-chlorobenzyl)amino]-9-cyclopentylpurine

https://huagongshe.com/reaction/478471

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Chlorophenyl)(cyclopropyl)methanamineHCID 5155531—
Reactant2,6-dichloro-9-cyclopentyl-9H-purineHCID 10801116—
SolventTriethylamineHCID 8471—
Product2-Chloro-6-[(alpha-cyclopropyl-4-chlorobenzyl)amino]-9-cyclopentylpurineHCID 18002077—

Reaction Steps

2-Chloro-6-[(α-cyclopropyl-4-chlorobenzyl)amino]-9-cyclopentylpurine is prepared from 2,6-dichloro-9-cyclopentylpurine, α-cyclopropyl-4-chlorobenzylamine, and triethylamine essentially as described above in Example 1, Scheme A, step b.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06642231B2
Source datasetuspto-grants-2003_11
ORD IDord-06c9306cd5284432ab90be0975c147ff
Source noteuspto-grants-2003_11