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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 478508Generated: November 1, 2026

3-(Chloromethyl)pyridine hydrochloride → 1-(pyridin-3-ylmethyl)piperidin-4-one

https://huagongshe.com/reaction/478508

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Chloromethyl)pyridine hydrochlorideHCID 23394—
Reactant4-PiperidoneHCID 33721—
Product1-(pyridin-3-ylmethyl)piperidin-4-oneHCID 6421624—

Reaction Steps

1-(3-Pyridinylmethyl)-4-piperidone is prepared from 4-piperidone and 3-picolyl chloride hydrochloride essentially as described above in Example 38, Scheme C, step a.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06642231B2
Source datasetuspto-grants-2003_11
ORD IDord-1532fc92196c472c882b2fca95be361b
Source noteuspto-grants-2003_11