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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 478576Generated: October 30, 2026

4-Piperidone → 1-(1H-Benzimidazol-2-ylmethyl)-4-piperidinone

https://huagongshe.com/reaction/478576

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-PiperidoneHCID 33721—
Reactant2-ChloromethylbenzimidazoleHCID 78571—
Product1-(1H-Benzimidazol-2-ylmethyl)-4-piperidinoneHCID 11791004—

Reaction Steps

1-(2-Benzimidazolyl)methyl4-piperidone is prepared from 4-piperidone and 2-(chloromethyl)benzimidazole essentially as described above in Example 38, Scheme C, step a.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06642231B2
Source datasetuspto-grants-2003_11
ORD IDord-ef9443e79b9e4a84adbfb952e8f12ca7
Source noteuspto-grants-2003_11