反应详情

4-(4-Benzyl-piperazin-1-yl)-benzoic acid methyl ester (19.4 mmol) is dissolved in methanol (150 ml) and Pd/charcoal is added (0.6 g). The mixture is stirred in a hydrogen atmosphere until consumption has ceased. The catalyst is filtered off and the filtrate evaporated. The residue is suspended in diethylether/pentane and the solid filtered of and dried (vacuum). A powder with mp. 95-97° C. is obtained.

1. filtrationThe catalyst is filtered off
2. customthe filtrate evaporated
3. filtrationthe solid filtered of and
4. customdried (vacuum)
5. customA powder with mp. 95-97° C. is obtained