HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → HCID 86587285, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | 3,5-Bis(trifluoromethyl)benzaldehyde | HCID 136247 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 86587285 | HCID 86587285 | — |
Reaction Steps
A solution of 3,5-bis(trifluoromethyl)-benzaldehyde (412 μL) in dry THF (5 mL) was added dropwise to a solution of methylamine (2M in MeOH—3.12 mL) in dry THF (5 mL) at 23° C. under a nitrogen atmosphere. The reaction mixture was stirred overnight, then the solvent was evaporated in vacuo to give the title compound (385 mg) as a colourless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06642240B2 |
| Source dataset | uspto-grants-2003_11 |
| ORD ID | ord-ecc701e8c31641e7a059507f54147638 |
| Source note | uspto-grants-2003_11 |