Nitric Acid → HCID 22064513, compound

HRID 478687Notes

Reaction equation

HRID 478687 reaction equation
[NH2:1][C:2]1[C:3]([C:12]([OH:14])=[O:13])=[CH:4][C:5]2[C:10]([CH:11]=1)=[CH:9][CH:8]=[CH:7][CH:6]=2.[N+:15]([O-:18])(O)=[O:16].[C:19](OC(=O)C)(=[O:21])[CH3:20]>>[C:19]([NH:1][C:2]1[C:3]([C:12]([OH:14])=[O:13])=[CH:4][C:5]2[C:10]([C:11]=1[N+:15]([O-:18])=[O:16])=[CH:9][CH:8]=[CH:7][CH:6]=2)(=[O:21])[CH3:20]

Participants

4

Reactant 3

HCID 944Nitric AcidHCID 7918Acetic AnhydrideHCID 222443-Amino-2-naphthoic acid

Product 1

HCID 22064513HCID 22064513, compound

Procedure

A solution of 5 g of 3-amino-2-naphthalenecarboxylic acid in 40 ml of acetic anhydride is stirred at ambient temperature for 30 minutes and then 5 ml of nitric acid are added dropwise. The reaction mixture is then stirred in an ice bath for 7 days and is then poured onto ice. The precipitate formed is filtered off, washed with water and then dried and rinsed with 40 ml of methanol, allowing the expected product to be isolated after drying.

Workup

  1. additionis then poured onto ice
  2. customThe precipitate formed
  3. filtrationis filtered off
  4. washwashed with water
  5. customdried
  6. washrinsed with 40 ml of methanol
  7. customto be isolated
  8. customafter drying

Sources & evidence

ORD record
ord-f673120fe9d14f37b72fad2aff192b3d
Source dataset
uspto-grants-2003_11
Patent number
US06642248B2

Reaction notes

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