HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 3-(pyridin-2-yl)acrylate → Ethyl 3-(pyridin-2-yl)propanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 3-(pyridin-2-yl)acrylate | HCID 370265 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Ethyl 3-(pyridin-2-yl)propanoate | HCID 347337 | 88.3% |
Reaction Steps
To a suspension of ethyl 3-(pyridin-2-yl)acrylate (2.8 g) in methanol (150 ml) was added 10% palladium on carbon (230 mg) and the mixture was stirred under hydrogen gas atmosphere for 3 hours at room temperature and then filtered to remove an insoluble. Evaporation of solvent from the filtrate yielded ethyl 3-(pyridin-2-yl)propionate (2.5 g, 88%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06642250B2 |
| Source dataset | uspto-grants-2003_11 |
| ORD ID | ord-d2eec73c321b44bebd6603415d0838ca |
| Source note | uspto-grants-2003_11 |