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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 478793Generated: October 26, 2026

(4-Nitrophenyl)acetic acid → 2-[(4Nitrophenyl)acetamido]butyric acid iso-butyl ester

https://huagongshe.com/reaction/478793

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Nitrophenyl)acetic acidHCID 4661—
ReactantIsobutyl 2-aminobutyrateHCID 13743360—
Product2-[(4Nitrophenyl)acetamido]butyric acid iso-butyl esterHCID 53795505—

Reaction Steps

Following General Procedure I above and using 4-nitrophenylacetic acid (Aldich) and iso-butyl 2-aminobutyrate (prepared following General Procedure J above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure. NMR data was as follows:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06642261B2
Source datasetuspto-grants-2003_11
ORD IDord-bc62161f45b843bebe4177b50058a0ab
Source noteuspto-grants-2003_11