HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Fluorophenylacetic acid → 2-[(3-Fluorophenyl)acetamido]butyric acid isobutyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Fluorophenylacetic acid | HCID 67617 | — |
| Reactant | Isobutyl 2-aminobutyrate | HCID 13743360 | — |
| Product | 2-[(3-Fluorophenyl)acetamido]butyric acid isobutyl ester | HCID 54019925 | — |
Reaction Steps
Following General Procedure I above and using 3-fluorophenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared rbllowing General Procedure J above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure. NMR data was as follows:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06642261B2 |
| Source dataset | uspto-grants-2003_11 |
| ORD ID | ord-72e419828d474e629fce07d1dcd8e4a0 |
| Source note | uspto-grants-2003_11 |