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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 478817Generated: November 1, 2026

3-(Methylthio)phenylacetic acid → N-[(3-methylthiophenyl)acetyl]alanine Iso-butyl Ester

https://huagongshe.com/reaction/478817

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Methylthio)phenylacetic acidHCID 2737461—
Reactant2-methylpropyl (2S)-2-aminopropanoateHCID 13743556—
ProductN-[(3-methylthiophenyl)acetyl]alanine Iso-butyl EsterHCID 15481777—

Reaction Steps

Following General Procedure I above, and using 3-methylthiophenylacetic acid (CAS# 18698-73-2) and alanine iso-butyl ester (prepared following General Procedure J above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06642261B2
Source datasetuspto-grants-2003_11
ORD IDord-d7376b08bb584b76bfc5fa3dada63890
Source noteuspto-grants-2003_11