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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 478818Generated: November 1, 2026

2-(1-Benzofuran-2-yl)acetic acid → N-[(benzofuran-2-yl)acetyl]alanine Iso-butyl Ester

https://huagongshe.com/reaction/478818

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(1-Benzofuran-2-yl)acetic acidHCID 11105888—
Reactant2-methylpropyl (2S)-2-aminopropanoateHCID 13743556—
ProductN-[(benzofuran-2-yl)acetyl]alanine Iso-butyl EsterHCID 15481779—

Reaction Steps

Following General Procedure I above, and using benzofuran-2-ylacetic acid (Maybridge) and alanine iso-butyl ester (prepared following General Procedure J above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06642261B2
Source datasetuspto-grants-2003_11
ORD IDord-b6c2405f9b794d76ba1f6dfecc67fab6
Source noteuspto-grants-2003_11