HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Thiophenacetic acid → N-[(3thienyl)acetyl]alanine Iso-butyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Thiophenacetic acid | HCID 23404 | — |
| Reactant | 2-methylpropyl (2S)-2-aminopropanoate | HCID 13743556 | — |
| Product | N-[(3thienyl)acetyl]alanine Iso-butyl Ester | HCID 53969374 | — |
Reaction Steps
Following General Procedure I above, and using 3-thiopheneacetic acid (Aldrich) and alanine iso-butyl ester (prepared following General Procedure J above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure. NMR data was as follows:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06642261B2 |
| Source dataset | uspto-grants-2003_11 |
| ORD ID | ord-8aa8281fb78a4e809766d844bb8d243a |
| Source note | uspto-grants-2003_11 |