HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Nitrophenylacetic acid → N-[(3-nitrophenyl)acetyl]-alanine iso-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Nitrophenylacetic acid | HCID 15876 | — |
| Reactant | 2-Methylpropyl (2S)-2-aminopropanoate hydrochloride | HCID 86584981 | — |
| Product | N-[(3-nitrophenyl)acetyl]-alanine iso-butyl ester | HCID 54157293 | — |
Reaction Steps
Following General Procedure H above and using 3-nitrophenylacetic acid (Aldrich) and L-alanine iso-butyl ester hydrochloride (from Example B above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by recrystallization from butyl chloride. NMR data was as follows:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06642261B2 |
| Source dataset | uspto-grants-2003_11 |
| ORD ID | ord-5c2d56646619431b8dacdf642c59c8d6 |
| Source note | uspto-grants-2003_11 |